Caspase 8 (CASP8, CASP-8, ALPS2B, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like Protease, FADD-like ICE, FLICE, FLJ17672, ICE-like Apoptotic Protease 5, MORT1-associated Ced-3 Homolog, MACH, MCH5, MGC78473)
Product Sizes
50ug
£480.00
C2087-34F-50UG
About this Product
- SKU:
- C2087-34F
- Application:
- Immunoprecipitation, Western Blot
- translate.label.attr.clone:
- 6D221 (C15)
- Clonality:
- Monoclonal
- Extra Details:
- Caspase-8 (FLICE, MACH, Mch5) is a member of the ICE/CED-3 family of cysteine proteases. It contains two death domains and interacts with FADD (MORT1) and the Fas Ligand induced Death Inducing Surface Complex’ (DISC). This complex is involved in the signal transduction that initiates the apoptotic protease cascade in many cell lines. Applications: Suitable for use in Immunocytochemistry, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml Optimal dilution to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to aa181-478 from human caspase-8.
- Isotype:
- IgG2b
- Physical State:
- Supplied as a liquid in PBS, 0.02% sodium azide, 10% glycerol.
- Purity:
- Purified by Protein G affinity chromatography from concentrated hybridoma tissue culture supernatant.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes the p18 subunit of human caspase-8.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies:Monoclonal Antibody
