Cadherin P
Product Sizes
50ug
£496.00
C0108-37J-50UG
About this Product
- SKU:
- C0108-37J
- Application:
- Western Blot, Immunohistochemistry
- translate.label.attr.clone:
- 3G51
- Clonality:
- Monoclonal
- Extra Details:
- P-cadherin is a 120kD Ca2+-dependent cell adhesion molecule, which appears to be expressed in cells having high growth activity and/or high differentiation potential. In the early mouse embryo, P-cadherin has been detected in the extra-embryonic ectoderm, visceral endoderm, Iateral plate mesoderm, and notocord. In the late embryo, P-cadherin is detected in the placenta, epidermis and other epithelial tissues, the pigmented retina, and the mesothelium. P-cadherin displays a rather unique distribution pattern in human tissues in that its expression is not detected in placental tissue. In humans, expression is restricted to epithelial tissues where it appears to be restricted to the basal or lower layers of stratified epithelia. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Also suitable as an inhibitor of P-cadherin dependent cell-cell contact. Other applications not tested. Recommended Dilutions: Western Blot: 5-10ug/ml Immunohistochemistry (Frozen): 5-10ug/ml Inhibition of P-cadherin-dependent cell-cell contact: 100ug/ml Optimal dilutions to be determined by the researcher. Hybridoma: Myeloma cell line P3-X63-Ag8-U1 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Epidermoid carcinoma cell line A431.
- Isotype:
- IgG1
- Physical State:
- Supplied as a liquid in TBS, 1% BSA.
- Purity:
- Purified by ammonium sulfate precipitation and anion exchange chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human P Cadherin.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
