Bcl 2 Modifing Factor, aa1-129, Recombinant, Human (Bmf, Bcl2 modifying factor, isoform 3)
Product Sizes
50ug
£651.00
B0807-08A-50UG
About this Product
- SKU:
- B0807-08A
- Extra Details:
- Bcl2 modifying factor, also known as BMF belongs to the Bcl2 protein family of apoptosis mediators. Bmf is constitutively expressed in many tissues. This protein contains a single Bcl2 homology domain 3 (BH3), and has been shown to bind Bcl2 proteins and function as an apoptotic activator. Also, BMF is a key molecule for histone deacetylase (HDAC) inhibitors which alters the balance between acetylation and deacetylation, significantly increasing histone acetylation, while strongly inducing apoptosis in a variety of cancer cell types. Source: Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E.coli. Molecular Weight: 15.6kD (144aa) Endotoxin Level: ≤1EU/ug Sequence of amino acids: MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSP ASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Molecular Weight:
- 15.6
- Physical State:
- Supplied as liquid in 20mM Tris-HCl, pH7.5, 1mM DTT, 10% glycerol.
- Purity:
- ≥90% (SDS-PAGE)
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
