Bax (BCL2-associated X protein, Apoptosis regulator BAX, cytoplasmic isoform beta, Apoptosis regulator BAX, membrane isoform alpha, BAX protein, cytoplasmic isoform delta, BAX protein, cytoplasmic isoform gamma, BCL2L4)
Product Sizes
1mg
£812.00
B0175-02M-1MG
About this Product
- SKU:
- B0175-02M
- Application:
- Western Blot, Apoptosis
- Clonality:
- Polyclonal
- Extra Details:
- Bax belongs to Bcl-2 protein family and accelerates the apoptosis by binding to the repressor Bcl-2. It can form oligomers and targets mitochondrial membrane inducing an increase in the membrane permeability which leads to the release of cytochrome c from mitochondria and the activation of the caspase pathway. Bax is considered a tumor suppressor. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide (MDGSGEQPRGGGPTSSEQIMK) corresponding to aa1-21 of human Bax
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.2.
- Purity:
- Purified by Protein G affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Bax
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
