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Antibodies

ASAHL (N-Acylsphingosine Amidohydrolase-like)

Product Sizes
100ug
£825.00
A3597-42A-100UG
About this Product
SKU:
A3597-42A
Application:
Immunoprecipitation, Western Blot
translate.label.attr.clone:
9H66
Clonality:
Monoclonal
Extra Details:
ASAHL (N-acylsphingosine-amidohydrolase-like; also acid ceramidase-like protein) is a 30kD member of the acid ceramidase family. It is a secreted lysosomal glycoprotein that cleaves fatty acid amides such as palmitoylethanolamine. Human ASAHL is synthesized as a 359aa preproprecursor that contains a 28aa signal sequence, a 96aa prosegment, and a 30-31kD, 235 aa mature region that begins at Cys125. Multiple isoforms likely exist. One isoform shows a deletion of aa324-359, while another has a two aa substitution for aa 198-359. The human proform (aa29-359) is 78% aa identical to mouse ASAHL proform. Applications: Suitable for use in ELISA, Western Blot, and Immunoprecipitation. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml Western Blot: 1-2ug/ml Immunoprecipitation: 25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Host:
Mouse
Immunogen:
CHO-derived, recombinant human ASAHL aa29-359; Q02083.
Isotype:
IgG1
Physical State:
Supplied as a lyophilized powder in 0.2um sterile-filtered solution, PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
Purity:
Purified by Protein G affinity chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes human ASAHL.
Source:
human
Storage Conditions:
-20[o]C
Type:
Antibodies:Monoclonal Antibody