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Antibodies

Rabies virus Glycoprotein (FITC)

Product Sizes
50ug
£460.00
574132-50UG
About this Product
SKU:
574132
Application:
FLISA
Clonality:
Polyclonal
Extra Details:
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity). Applications: Suitable for use in FLISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to aa20-459 from rabies virus glycoprotein protein.
Isotype:
IgG
Physical State:
Supplied as a liquid in PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
Purity:
Purified by Protein G affinity chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes rabies virus G.
Source:
Rabies virus
Storage Conditions:
-20[o]C
Type:
Antibodies:Polyclonal Antibody