Glutathione S-transferase Mu 1, Recombinant, Human, aa1-218, His-Tag (GSTM1)
Product Sizes
50ug
£479.00
506174-50UG
About this Product
- SKU:
- 506174
- Extra Details:
- GSTM1, also known as glutathione S-transferase Mu 1, is members of the phase ll detoxification enzyme family. This protein is cytosolic protein that belongs to the mu class of the GST superfamily. The eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Also, it acts as a hormone binding protein and plays a role in maintaining hormone homeostasis in the body. Recombinant human GSTM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. Recombinant protein corresponding to aa1-218 of human GSTM, fused to His-tag at C-terminus, expressed in Baculovirus Molecular Weight: ~26.8kD (227aa), ~28-40kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: ADPMPMILGY WDIRGLAHAI RLLLEYTDSS YEEKKYTMGD APDYDRSQWL NEKFKLGLDF PNLPYLIDGA HKITQSNAIL CYIARKHNLC GETEEEKIRV DILENQTMDN HMQLGMICYN PEFEKLKPKY LEELPEKLKL YSEFLGKRPW FAGNKITFVD FLVYDVLDLH RIFEPKCLDA FPNLKDFISR FEGLEKISAY MKSSRFLPRP VFSKMAVWGN KHHHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Physical State:
- Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.2M sodium chloride, 2mM DTT, 0.1mM PMSF, 40% glycerol.
- Purity:
- ≥90% (SDS-PAGE). Endotoxin: ≤0.1EU/1ug (LAL)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C
- Supplier:
- United States Biological
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
