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Antibodies

Lambda Light Chain (Free and Bound)

Product Sizes
10ml
£863.00
474292-10ML
About this Product
SKU:
474292
Clonality:
Polyclonal
Extra Details:
In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Applications: Suitable for use in Immunoelectrophoresis. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Total Protein: 2.9g/dL Titer: 5.7mg/mL (IFCC) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Goat
Immunogen:
Purified human Lambda Light Chains.
Isotype:
IgG
Physical State:
Supplied as a liquid in Tris, pH 7.4, 0.5M sodium chloride, 0.09% sodium azide.
Purity:
Defibrinated, delipidated, fractionated and adsorbed by solid phase chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes Lambda Light Chains. Monospecific by IEP with neat antibody when tested against pooled human plasma and twice concentrated human serum. No reaction to Kappa Light Chains by Ouchterlony.
Source:
human
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Antibodies:Polyclonal Antibody