Doravirine (MK-1439)
Product Sizes
1mg
£298.00
447665-1MG
About this Product
- SKU:
- 447665
- CAS Number:
- 1338225-97-0
- Extra Details:
- Doravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits HIV reverse transcriptase (IC50 = 11nM).1 It inhibits the spread of wild-type HIV and K103N, Y181C, and K103N/Y181C mutant HIV strains in cells cultured with 50% normal human serum (IC95s = 19, 42, 25, and 54nM, respectively). Formulations containing doravirine have been used in the treatment of HIV-1 infection. Synonyms: 3-Chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile; MK-1439 CAS No: 1338225-97-0 Molecular Formula: C17H11ClF3N5O3 Molecular Weight: 425.75 Purity: ≥98% Appearance: White to off-white solid Solubility: Soluble in DMSO and Methanol (Slightly) Melting Point: 276-278°C Infared Radiation: Conforms to structure NMR: Conforms to structure Storage and Stability: May be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with DMSO. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Molecular Weight:
- 425.75
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Inhibitors
