CD52, Recombinant, Human, aa1-36, hIgG-His-Tag (CAMPATH-1 Antigen, CD52, CDW52, EDDM5)
Product Sizes
20ug
£607.00
396847-20UG
About this Product
- SKU:
- 396847
- Extra Details:
- CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes- derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to a1-36 of human CD52, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~28.2kD (251aa), ~28-40kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molecular Weight:
- 28.2
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
- Purity:
- ≥95% (SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 4[o]C/-20[o]C
- Supplier:
- United States Biological
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
