CD274, Recombinant, Human, aa19-238, hIgG-His-Tag (Programmed Cell Death 1 Ligand 1, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1)
Product Sizes
50ug
£607.00
377734-50UG
About this Product
- SKU:
- 377734
- Extra Details:
- CD274, also known as programmed cell death 1 ligand 1 isoform, is a member of the growing B7 family of immune molecules. This protein is involved in the regulation of cellular and humoral immune responses. It suppresses T cell activation and proliferation and induces the apoptosis of activated T cells. Also, it plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development. Source: Recombinant protein corresponding to aa19-238 from human CD274, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~52.5kD (462aa), 50-70kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADLFTVTVPK DLYVVEYGSN MTIECKFPVE KQLDLAALIV YWEMEDKNII QFVHGEEDLK VQHSSYRQRA RLLKDQLSLG NAALQITDVK LQDAGVYRCM ISYGGADYKR ITVKVNAPYN KINQRILVVD PVTSEHELTC QAEGYPKAEV IWTSSDHQVL SGKTTTTNSK REEKLFNVTS TLRINTTTNE IFYCTFRRLD PEENHTAELV IPELPLAHPP NERLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molecular Weight:
- 52.5
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 20% glycerol.
- Purity:
- ≥95% (SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
