PCDH1 (Protocadherin 1, CNR1, Pc42, Cadherin Related Neuronal Receptor 1, Cadherin-Like 1, Protocadherin-42)
Product Sizes
200ul
£531.00
364535-200UL
About this Product
- SKU:
- 364535
- Application:
- Immunohistochemistry
- Clonality:
- Polyclonal
- Extra Details:
- Cadherins are a group of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. By PCR of rat, mouse, and human neural cell cDNA with degenerate primers based on conserved regions of the cadherin extracellular domain, Sano et al. (1993) isolated partial cDNAs encoding pc42 and pc43 (PCDH2). They used the partial cDNAs to screen a human brain library and recovered cDNAs corresponding to the entire coding sequence of both genes. Like typical cadherins, both pc42 and pc43 contain an N-terminal extracellular domain, a transmembrane domain, and a C-terminal cytoplasmic region. The extracellular domains of pc42 and pc43 contain 7 and 6 repeats, respectively, of a subdomain that is very similar to those of cadherins, but with characteristic properties. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa246-517 of mouse PCDH1, expressed in E. coli.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes mouse PCDH1.
- Source:
- mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
