OASL (2',5'-Oligoadenylate Synthetase Like Protein, TRIP14, p59OASL, 59kD 2'-5'-oligoadenylate synthase-like protein, Thyroid receptor-interacting protein 14)
Product Sizes
200ul
£626.00
364468-200UL
About this Product
- SKU:
- 364468
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- The thyroid hormone receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. In a screen for TR-interacting proteins (TRIPs), The predicted 514aa p59OASL shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. Northern blot analysis revealed that p59OASL is expressed in most tissues, with the highest levels in primary blood leukocytes and other hematopoietic system tissues, colon, and stomach. p59OASL transcription is induced by interferon. The p59OASL gene contains 6 exons. Exons 1-5 are similar in structure to exons 3-7 of OAS1, suggesting that the 2 genes arose from a duplication of an ancestral gene. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-2ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa2-244 of human OASL, expressed in E. coli.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in 0.01M PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human OASL.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
