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Antibodies

NUP210 (Nucleoporin 210kD, POM210, gp210, Nuclear Pore Glycoprotein 210, Nuclear envelope pore membrane protein POM 210, Pore membrane protein of 210kD)

Product Sizes
200ul
£554.00
364450-200UL
About this Product
SKU:
364450
Application:
Western Blot, Immunohistochemistry
Clonality:
Polyclonal
Extra Details:
Nuclear pore glycoprotein-210 (gp210) is an essential trafficking regulator in the eukaryotic nuclear pore complex. Gp-210 anchors the pore complex to the nuclear membrane. and protein tagging reveals its primarily located on the luminal side of double layer membrane at the pore. A single polypeptide motif of gp210 is responsible for sorting to nuclear membrane, and indicate the carboxyl tail of the protein is oriented toward the cytoplasmic side of the membrane. The deduced protein contains 1,886aa. Northern blot analysis detected a 7.5-kb transcript. In situ hybridization detected preferential expression in epithelial cells. In kidney, expression was seen in both the epithelium derived from the ureteric tree and the mesenchyme-derived epithelium. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-5ug/ml Immunohistochemistry (Paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to aa1288-1449 of human NUP210, expressed in E. coli.
Isotype:
IgG
Physical State:
Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Purity:
Purified by Protein A and peptide affinity chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes human NUP210. Species Crossreactivity: mouse
Source:
human
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Antibodies:Polyclonal Antibody