MCP2 (Monocyte Chemotactic Protein 2, CCL8, CCL-8, SCYA8, MCP-2, HC14, Chemokine C-C-Motif Ligand 8, Small Inducible Cytokine Subfamily A(Cys-Cys)Member 8, Monocyte Chemoattractant Protein 2)
Product Sizes
200ul
£544.00
364089-200UL
About this Product
- SKU:
- 364089
- Application:
- Immunohistochemistry
- Clonality:
- Polyclonal
- Extra Details:
- Chemokine (C-C motif) ligand 8 (CCL8) is a small cytokine belonging to the CC chemokine family that was once called monocyte chemotactic protein-2 (MCP-2). The CCL8 protein is produced as a precursor containing 109aa which is cleaved to produce mature CCL8 containing 75aa MCP-2 is chemotactic for and activates a many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B and CCR5. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa1-99 of human MCP2, expressed in E. coli
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol
- Purity:
- Purified by Protein A and peptide affinity chromatography
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human MCP2
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
