GCNF (Germ Cell Nuclear Factor, NR6A1, NR6-A1, 6, Group A, Member 1, Retinoid receptor-related testis-specific receptor)
Product Sizes
200ul
£639.00
363243-200UL
About this Product
- SKU:
- 363243
- Application:
- Immunohistochemistry
- Clonality:
- Polyclonal
- Extra Details:
- The germ cell nuclear factor (GCNF) protein, also known as RTR (retinoid receptor-related testis-associated receptor), is a member of the nuclear receptor family of intracellular transcription factors and is encoded by the NR6A1 gene (nuclear receptor subfamily 6, group A, member 1). In adults, GCNH is expressed mainly in the germ cells of gonads and is involved in the regulation of embryogenesis and germ cell differentiation. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses three alternatively spliced transcript variants. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa282-480 of human GCNF, expressed in E. coli.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human GCNF.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies:Polyclonal Antibody
