ENA78 (Epithelial Neutrophil Activating Peptide 78, CXCL5, SCYB5, Chemokine C-X-C-Motif Ligand 5, Small Inducible Cytokine Subfamily B(Cys-X-Cys),Member 5, Neutrophil-activating peptide ENA-78)
Product Sizes
200ul
£466.00
362967-200UL
About this Product
- SKU:
- 362967
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Extra Details:
- ENA-78 is a CXC chemokine that was originally isolated from media conditioned by the growth of a mouse lung type-II alveolar epithelial cell line (A549) stimulated by IL-1 or TNF. The full-length cDNA encodes a 114aa residue precursor protein with a 36aa residue signal peptide that is cleaved to generate the 78aa residue secreted protein. ENA-78 shares significant aa sequence identity with NAP-2 (53%), GRO,, and (52%, 48% and 51%, respectively), and IL-8 (22%). The gene for ENA-78 has been mapped to chromosome 4q13-q21. Like other CXC chemokines, ENA-78 is a neutrophil attractant and activator in vitro. Based on cross- desensitization experiments, it has been suggested that ENA-78 activity can be mediated through the IL-8 receptor system. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Ala41-Asn114 of human ENA78, expressed in E. coli.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human ENA78.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
