2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-glucopyranose
Product Sizes
5g
£501.00
292479-5G
About this Product
- SKU:
- 292479
- CAS Number:
- 7784-54-5, 14086-90-9
- Extra Details:
- 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-glucopyranose (2AAT) is a synthetic nucleoside that binds to the same sequence of n-acetylgalactosamine in the cell wall of Gram positive bacteria. It was found to be effective against bacterial strains that produce beta lactamase enzymes. 2AAT has been shown to inhibit the growth of Gram positive bacteria and is able to penetrate tissues. It also prevents bacterial DNA gyrase and topoisomerase IV from binding with their respective substrates. 2AAT is made up of four parts: two ribose molecules, one deoxyribose molecule and one acetamido group. This last part is what makes it bind to the bacterial cell wall and inhibits protein synthesis by preventing mRNA from being translated into proteins. Synonyms: 1,2,3,4,6-Penta-O-acetyl-a-D-glucosamine; a-D-Glucosamine pentaacetate; 2-(Acetylamino)-2-deoxy-a-D-glucopyranose 1,3,4,6-tetraacetate CAS No: 7784-54-5, 14086-90-9 Molecular Formula: C₁₆H₂₃NO₁₀ Molecular Weight: 389.35 Purity: ≥95% Appearance: White to off-white powder Solubility: Readily soluble in various polar and organic solvents, but it has limited to no solubility in water. H NMR: Conforms to reference Melting Point: 187-189°C (lit) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Molecular Weight:
- 389.35
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C
- Supplier:
- United States Biological
- Type:
- Molecular Biology Reagents:Nucleotides
