PLGF-1, Recombinant, Human (Placental Growth Factor1, PGFL, PLGF)
Product Sizes
25ug
£492.00
215087-25UG
About this Product
- SKU:
- 215087
- Extra Details:
- Placental growth factor (PLGF) is a dimeric glycoprotein and member of the vascular endothelial growth factor (VEGF) family, involved in angiogenesis, and the stimulation of endothelial cell proliferation and migration. The three isoforms PLGF-1, PLGF-2 and PLGF-3 are present in most placental tissues and act through binding to the VEGFR-1/FLT1 receptor. PLGF has become a focus area in the study of angiogenesis and inflammatory diseases such as rheumatoid arthritis and psoriasis, and PLGF is used as a biochemical marker in cardiovascular disease, and also detected at reduced levels during preeclampsia. Recombinant protein corresponding to human Placental Growth Factor expressed in E. coli Molecular Weight: ~29.7kD Amino Acid Sequence (Monomer): MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 1-10ng/ml. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molecular Weight:
- 29.7
- Physical State:
- Supplied as a lyophilized powder from 10mM sodium phosphate. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. For extended storage, the additions of 0.1% bovine serum albumin (BSA
- Purity:
- ≥95% (SDS-PAGE, HPLC). Endotoxin: ≤0.1 ng/ug (<1EU/ug)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
