BAD (Bcl-2 Antagonist of Cell Death, BBC6, BCL2L8)
Product Sizes
100ug
£748.00
145396-100UG
About this Product
- SKU:
- 145396
- Application:
- Western Blot
- translate.label.attr.clone:
- 64103
- Clonality:
- Monoclonal
- Extra Details:
- The Bcl-2 family of proteins consists of both inhibitors and promoters of apoptosis. The relative ratios of pro- and anti-apoptotic Bcl-2 family proteins determine the sensitivity or resistance of cells to a variety of apoptotic signals. The pro-apoptoptic Bad (Bcl-2-antagonist of cell death) heterodimerizes strongly with Bcl-x, less strongly with Bcl-2, and not at all with Bax, Bcl-xS, Mcl-1, A1, or itself. When Bad dimerizes with Bcl-xL, Bax is displaced and its apoptosis-inducing ability is restored. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to mouse Bad, E. coli- derived
- Isotype:
- IgG2a
- Physical State:
- Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute in sterile PBS.
- Purity:
- Purified by Protein A or G affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes endogenous mouse Bad in Western blots.
- Source:
- mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
