IL10 (Interleukin-10, IL-10, Interleukin 10, Cytokine Synthesis Inhibitory Factor, CSIF) (Biotin)
Product Sizes
100ul
£722.00
143595-BIOTIN-100UL
About this Product
- SKU:
- 143595-BIOTIN
- Application:
- Western Blot
- translate.label.attr.clone:
- 14G8
- Clonality:
- Monoclonal
- Extra Details:
- The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Applications: Suitable for use in ELISA, Western Blot, Neutralization. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Host:
- Mouse
- Immunogen:
- Recombinant human IL-10 expressed in E.coli.
- Isotype:
- IgG1,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
- Purity:
- Purified by Protein A affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human IL-10.
- Source:
- human
- Storage Conditions:
- 4[o]C/-20[o]C
- Type:
- Antibodies:Monoclonal Antibody
