CD178 (APTL, FASL, FAS-ligand, CD95L, TNFSF6, TNLG1A)
Product Sizes
100ug
£479.00
046256-100UG
About this Product
- SKU:
- 046256
- Application:
- Immunoprecipitation, Flow Cytometry, Western Blot
- translate.label.attr.clone:
- NOK-1
- Clonality:
- Monoclonal
- Extra Details:
- CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- L5178Y mouse T lymphoma cells expressing recombinant human CD178
- Isotype:
- IgG1
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
- Purity:
- Purified by Protein A affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human CD178,
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
