Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout

ABT-263(Navitoclax)

Product Sizes
25 mg
£402.00
F7141-25MG
About this Product
SKU:
F7141
Buffer:
Powder; no buffer
Extra Details:
UMI-77 is a selective Mcl-1 inhibitor by binding of the BH3-binding groove of Mcl-1, by which it blocks the interactions of Bax/Mcl-1 and Bak/Mcl-1. UMI-77 inhibits growth of pancreatic cancer cells with IC50 of 3.4, 4.4, 12.5, 16.1, and 5.5 μM for BxPC-3, Panc-1, MiaPaCa-2, AsPC-1 and Capan-2 cells, respectively. UMI-77 induces apoptosis of various pancreatic cancer cell lines.
Molecular Weight:
468.34 g/mol
Shipping Conditions:
Ambient
Source:
chemical synthesis
Storage Conditions:
-20 0C
Supplier:
UBP Bio
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules