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Necrostatin-1

Product Sizes
5 mg
£133.00
F7100-5MG
About this Product
SKU:
F7100
Buffer:
Powder; no buffer
Extra Details:
Necrostatin-1 is a potent inhibitor of necroptosis, a programmed and caspase-independent cell death mechanism. The death domain receptor-associated serine/threonine kinase RIP1 is essential for TNF-induced necrosis. Necrostatin-1 inhibits RIP1 and blocks TNFα-induced necrosis of FADD-deficient Jurkat cells with an EC50 value of 490 nM.
Molecular Weight:
259.33 g/mol
Shipping Conditions:
Ambient
Source:
chemical synthesis
Storage Conditions:
-20 0C
Supplier:
UBP Bio
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules