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SBI-0206965

Product Sizes
5 mg
£157.00
F6210-5MG
About this Product
SKU:
F6210
Buffer:
Powder; no buffer
Extra Details:
SBI-0206965 is a potent inhibitor of the autophagy kinase ULK1. It inhibits ULK1 and ULK2 kinases with IC₅₀ of 108 nM and 711 nM, respectively. ULK1 is a serine/threonine kinase acting upsteam of PI3K to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation. SBI-0206965 suppresses ULK1-mediated phosphorylation events in cells, regulating autophagy and cell survival.
Molecular Weight:
489.32 g/mol
Shipping Conditions:
Ambient
Source:
chemical synthesis
Storage Conditions:
-20 0C
Supplier:
UBP Bio
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules