GDC-0068(RG7440)
Product Sizes
5 mg
£168.00
F6170-5MG
About this Product
- SKU:
- F6170
- Buffer:
- Powder; no buffer
- Extra Details:
- GDC-0068 (RG7440 or Ipatasertib) is a novel, ATP-competitive Akt1/2/3 inhibitor with IC50 values of 5 nM, 18 nM and 8 nM, respectively. GDC-0068 selectively inhibits cell cycle progression and viability of cancer cell lines driven by PI3K/Akt signaling pathway, including those with defects of the tumor suppressor PTEN, oncogenic mutations in PIK3CA, and amplification of HER2. GDC-0068 blocks the phosphorylation of multiple downstream targets of Akt in human cancer cell lines.
- Molecular Weight:
- 458 g/mol
- Shipping Conditions:
- Ambient
- Source:
- chemical synthesis
- Storage Conditions:
- -20 0C
- Supplier:
- UBP Bio
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
