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PR-619

Product Sizes
5 mg
£151.00
F2110-5MG
About this Product
SKU:
F2110
Buffer:
Powder; no buffer
Extra Details:
A cell-permeable pan deubiquitinating enzyme inhibitor that is known to inhibit ATXN3, BAP1, JOSD2, OTUD5, UCH-L1, UCH-L3, UCH-L5/UCH37, USP1, 2, 4, 5, 7, 8, 9X, 10, 14, 15, 16, 19, 20, 22, 24, 28, 47, 48, VCIP135, YOD1, as well as deISGylase PLpro, deNEDDylase DEN1, and deSUMOlyase SENP6. PR-619 inhibits many deubiquitinating enzymes in the 5-20µM range. Treating cells with PR-619 results in the accumulation of both ubiquitin and sumo-conjugated proteins.
Molecular Weight:
223.28 g/mol
Shipping Conditions:
Ambient
Source:
chemical synthesis
Storage Conditions:
-20 0C
Supplier:
UBP Bio
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules