b-AP15
Product Sizes
10 mg
£233.00
F2101-10MG
About this Product
- SKU:
- F2101
- Buffer:
- Powder; no buffer
- Extra Details:
- LDN-57444 is a potent small chemical inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1, IC50 = 0.88 μM). UCHL1 functions to generate free ubiquitin from ubiquitin precursors. Loss of UCH-L1 activity causes apoptosis due to an impaired ubiquitin-proteasome pathway. LDN-57444-induced reduction of free ubiquitin could increase spine size while decreasing spine density in hippocampal neurons.
- Molecular Weight:
- 397.6 g/mol
- Shipping Conditions:
- Ambient
- Source:
- chemical synthesis
- Storage Conditions:
- -20 0C
- Supplier:
- UBP Bio
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:ldn57444-1872.html
