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6xHis-Nedd8

Product Sizes
500 ug
£423.00
E4100-500UG
About this Product
SKU:
E4100
Buffer:
20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
Extra Details:
Nedd8 is an 81 amino acid Ub-like protein. It is conjugated to protein substrates in much the same way as Ub, using the E1, E2, E3 cascade. The specific E1 used is a heterodimer of APPBP1/UBA3. Two E2s have been discovered to follow called Ubc12 and Ube2F. Neddylation causes conformational change of the Cullin protein in the E3 called cullin-RING ligases (CRLs), which enhances the E3 Ub ligase activity of CRLs.
Molecular Weight:
9 kDa
Shipping Conditions:
Dry Ice
Source:
E. coli recombinant
Storage Conditions:
- 80 0C
Supplier:
UBP Bio
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules