6xHis-UbE2A (Rad6A)
Product Sizes
100 ug
£633.00
C1101-100UG
About this Product
- SKU:
- C1101
- Buffer:
- 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
- Extra Details:
- Ube2A is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 95% amino acid sequence identity with Ube2B. One function of Ube2A involves the formation of Ube2A/Rad18 (an E3 enzyme) complex to monoubiquitinate proliferating cell nuclear antigen (PCNA) thus activating it to repair DNA damage. Ube2A is an X – chromosomal gene. Mutations in Ube2A have been linked to intellectual disability (ID), severely impaired speech, amongst other symptoms.
- Molecular Weight:
- 17.1 kDa
- Shipping Conditions:
- Dry Ice
- Source:
- E. coli recombinant
- Storage Conditions:
- - 80 0C
- Supplier:
- UBP Bio
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
