Choline Acetyltransferase Antibody: HRP
Product Sizes
100 ug
SPC-706D-HRP-100UG
About this Product
- SKU:
- SPC-706D-HRP
- Additional Names:
- CHAT, Choline acetyltransferase, Acetyl-CoA choline O-acetyltransferase, Choline acetylase, CLAT_HUMAN, CMS1A
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- 73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide, 0.23mM Citrate
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Concentration:
- 1 mg/ml
- Extra Details:
- Choline acetyltransferase (ChAT) catalyzes the synthesis of acetylcholine (ACh), a neurotransmitter essential for motor control, memory, and autonomic function. ChAT is selectively expressed in cholinergic neurons, making it a reliable marker for cholinergic system integrity. Loss of ChAT activity is a hallmark of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Down syndrome. Reduced ChAT expression correlates with cognitive decline and impaired synaptic transmission in affected brain regions. As a neuron-specific enzyme with a direct role in neurotransmitter synthesis, ChAT is both a diagnostic marker and a therapeutic target in disorders characterized by cholinergic dysfunction.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide from the N-terminal to the mid-protein of human Choline O-Acetyltrasferase
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Predicted molecular weight at ~82.5kDa. Observed molecular weights between 68-70kDa.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Polyclonal Antibody
