TLR4 Antibody

Product Sizes

12 ug

£58.00

SPC-200-12UG

100 ug

£301.00

SPC-200-100UG

About this Product

SKU:: SPC-200
Additional Names:: ARMD10 Antibody, CD284 Antibody, TLR 4 Antibody, TOLL Antibody, Toll like receptor 4 Antibody
Application:: FACS, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Clonality:: Polyclonal
Concentration:: 1 mg/ml
Extra Details:: The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa (6).
Host:: Rabbit
Purification:: Protein A Purified
Reactivities:: Human, Mouse
Shipping Conditions:: Blue Ice
Specificity:: Detects ~75-80kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag).
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
Type:: Antibody: Polyclonal Antibody

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