Cpn10 Antibody: Biotin
Product Sizes
100 ug
£400.00
SPC-193D-BI-100UG
About this Product
- SKU:
- SPC-193D-BI
- Additional Names:
- 10kDa Chaperonin, Chaperonin 10, Cpn 10, EPF, GROES, Heat Shock 10kD protein1, HSP10, HSPE1
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- 136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Concentration:
- 1 mg/ml
- Extra Details:
- Cpn10 (Chaperonin 10), a member of the HSP10 family, functions as a co-chaperone with HSP60 to facilitate proper protein folding and assembly. It is essential for maintaining proteostasis, particularly under stress conditions such as oxidative damage and inflammation. In the nervous system, Cpn10 supports mitochondrial protein folding and cellular resilience. Its identification as early pregnancy factor and presence in serum suggest systemic regulatory roles, potentially acting as a stress-responsive signaling molecule. Given the central role of protein misfolding in neurodegenerative diseases like Alzheimer's and Parkinson's, Cpn10 is a candidate for therapeutic exploration in modulating chaperone networks and preventing proteotoxicity.
- Host:
- Rabbit
- Immunogen:
- Human Cpn10 peptide AA 91-101
- Purification:
- Protein A Purified
- Reactivities:
- Amphibian, Bovine, Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects ~ 10kDa.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Polyclonal Antibody
