Cpn10 Antibody
Product Sizes
12 ug
SPC-193-12UG
100 ug
SPC-193-100UG
About this Product
- SKU:
- SPC-193
- Additional Names:
- 10kDa Chaperonin, Chaperonin 10, Cpn 10, EPF, GROES, Heat Shock 10kD protein1, HSP10, HSPE1
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS pH7.3, 0.02% sodium azide
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cpn10 (Chaperonin 10), a member of the HSP10 family, functions as a co-chaperone with HSP60 to facilitate proper protein folding and assembly. It is essential for maintaining proteostasis, particularly under stress conditions such as oxidative damage and inflammation. In the nervous system, Cpn10 supports mitochondrial protein folding and cellular resilience. Its identification as early pregnancy factor and presence in serum suggest systemic regulatory roles, potentially acting as a stress-responsive signaling molecule. Given the central role of protein misfolding in neurodegenerative diseases like Alzheimer's and Parkinson's, Cpn10 is a candidate for therapeutic exploration in modulating chaperone networks and preventing proteotoxicity.
- Host:
- Rabbit
- Immunogen:
- Human Cpn10 peptide AA 91-101
- Purification:
- Protein A Purified
- Reactivities:
- Amphibian, Bovine, Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects ~ 10kDa.
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/antibodies/polyclonal-antibodies/cpn10-antibody-spc-193/
