Amyloid Beta 1-42 Oligomer Antibody, Clone 1C1: Biotin
Product Sizes
100 ug
SMC-619D-BI-100UG
About this Product
- SKU:
- SMC-619D-BI
- Additional Names:
- Amyloid Beta 1-42 Oligomer, AB Beta1-42 Oligomer, Abeta Oligomers, Amyloid beta peptide 1-42, AB Beta42, Beta-amyloid protein 42, Beta-APP42, Amyloid beta A4 protein, APP, ABPP, APPI, Non-A4 component of amyloid precursor, Alzheimer disease amyloid protein
- Application:
- ELISA, Western Blot
- Buffer:
- 136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 1C1
- Clonality:
- Recombinant Monoclonal
- Conjugate:
- Biotin
- Concentration:
- 1 mg/ml
- Extra Details:
- Amyloid beta (AB Beta) peptide, particularly the 1-42 isoform (AB Beta1-42), plays a central role in the pathogenesis of Alzheimer's disease (AD). AB Beta is generated through proteolytic cleavage of the amyloid precursor protein (APP) and can self-assemble into a range of aggregated species, including oligomers, protofibrils, fibrils, and ultimately extracellular plaques. Among these, AB Beta1-42 oligomers are increasingly recognized as the most neurotoxic species, contributing to synaptic dysfunction, neuroinflammation, and cognitive decline. StressMarq's amyloid beta oligomer antibody has been validated for high specificity toward amyloid beta aggregates, distinguishing them from aggregated Tau and Alpha Synuclein proteins. This specificity is critical for accurately detecting early-stage, soluble aggregates that precede plaque formation and are believed to drive early neurodegenerative changes in AD. Tools that selectively recognize aggregated amyloid beta are essential for advancing both basic research and translational efforts in Alzheimer's disease.
- Host:
- Rabbit
- Immunogen:
- Amyloid beta 1-42 oligomers (StressMarq Catalog# SPR-488)
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Amyloid Beta Aggregates
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Recombinant Antibodies
