DENND4C Antibody: HRP
Product Sizes
100 ug
SMC-610D-HRP-100UG
About this Product
- SKU:
- SMC-610D-HRP
- Additional Names:
- DENN domain-containing protein 4C
- Application:
- Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- 73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide 0.23mM Citrate
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 3E8
- Clonality:
- Monoclonal
- Conjugate:
- HRP
- Concentration:
- 1 mg/ml
- Extra Details:
- DENND4C is a guanine nucleotide exchange factor (GEF) for Rab10, a small GTPase involved in vesicle trafficking and membrane recycling. DENND4C regulates GLUT4 translocation and interacts with the retromer complex, linking it to endosomal sorting and cellular metabolism. Mutations in DENND4C have been associated with neurodevelopmental syndromes such as Alkuraya-Kucinskas and Koolen-De Vries, suggesting a broader role in brain development and function. Its involvement in membrane trafficking pathways positions DENND4C as a candidate for investigation in neurodegenerative diseases characterized by endolysosomal dysfunction.
- Host:
- Mouse
- Immunogen:
- Full Length Human Recombinant Dennd4c protein
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects ~213 kDa.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
