4-Hydroxynonenal Antibody, Clone 12F7: RPE
Product Sizes
100 ug
£436.00
SMC-511D-RPE-100UG
About this Product
- SKU:
- SMC-511D-RPE
- Additional Names:
- 4-Hydroxynonenal Antibody, 4-Hydroxy Nonenal (4-HNE) Antibody, 4-Hydroxy Nonenal Antibody, 4-HNE Antibody, 4-hydroxy Hexenal Antibody, HNE Antibody, 4-hydroxy-2-nonenal Antibody
- Application:
- ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- pbs
- Clone:
- 12F7
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Concentration:
- 1 mg/ml
- Extra Details:
- 4-Hydroxy-2-nonenol (4-HNE) is an unsaturated aldehyde derived from lipid peroxidation. 4-HNE is an electrophile and reacts with protein nucleophiles such as cysteine, histine, and lysine (1). Low levels of 4-HNE promote cell survival via cellular antioxidant induction whereas higher levels lead to autophagy, apoptosis, and ultimately necrosis. 4-HNE has been linked to Alzheimer's disease, Parkinson's disease, cancer, cardiovascular diseases, diabetes, and liver disease.
- Host:
- Mouse
- Purification:
- Protein G Purified
- Reactivities:
- Wide/Non-species Specific
- Shipping Conditions:
- Blue Ice
- Specificity:
- Specific for 4-Hydroxynonenal (4-HNE) modified proteins. Does not detect free 4-Hydroxynonenal. Does not cross-react with 4-Hydroxy-2-hexenal, Acrolein, Crotonaldehyde, Hexanoyl Lysine, Malondialdehyde, or Methylglyoxal modified proteins.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody