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Antibodies

Alginate Antibody, Clone 3G4-1F5: ATTO 390

Product Sizes
100 ug
£538.00
SMC-209D-A390-100UG
About this Product
SKU:
SMC-209D-A390
Additional Names:
Alginate, a naturally derived polysaccharide from brown seaweed, is widely used in biomedical research due to its excellent biocompatibility, low immunogenicity, and ability to form hydrogels through ionic crosslinking with divalent cations such as calcium (Ca²⁺). In neuroscience and neurodegenerative disease research, alginate-based systems are gaining traction as advanced platforms for cell encapsulation, controlled drug delivery, and 3D neural tissue modeling. One of alginate's most impactful applications is in the formation of microspheres and scaffolds that enable sustained, localized delivery of neuroprotective proteins and therapeutic agents. This controlled release capability is critical for maintaining therapeutic concentrations in the brain microenvironment, particularly in diseases such as Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis (ALS), where targeted intervention is essential. Moreover, alginate hydrogels support the encapsulation and transplantation of neural stem cells and glial cells, preserving cell viability and function while minimizing immune rejection. These properties make alginate an ideal candidate for developing bioengineered neural tissues, in vitro brain models, and regenerative therapies aimed at restoring damaged neural circuits. As research advances, alginate continues to emerge as a key biomaterial in the design of next-generation neurotherapeutic strategies, offering promising avenues for both fundamental neuroscience and translational applications in neurodegenerative disease treatment.
Application:
Immunohistochemistry, Western Blot
Buffer:
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
CE/IVD:
RUO
translate.label.attr.clone:
3G4-1F5
Clonality:
Monoclonal
Conjugate:
ATTO 390
Concentration:
1 mg/ml
Extra Details:
Alginate, a naturally derived polysaccharide from brown seaweed, is widely used in biomedical research due to its excellent biocompatibility, low immunogenicity, and ability to form hydrogels through ionic crosslinking with divalent cations such as calcium (Ca²⁺). In neuroscience and neurodegenerative disease research, alginate-based systems are gaining traction as advanced platforms for cell encapsulation, controlled drug delivery, and 3D neural tissue modeling. One of alginate's most impactful applications is in the formation of microspheres and scaffolds that enable sustained, localized delivery of neuroprotective proteins and therapeutic agents. This controlled release capability is critical for maintaining therapeutic concentrations in the brain microenvironment, particularly in diseases such as Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis (ALS), where targeted intervention is essential. Moreover, alginate hydrogels support the encapsulation and transplantation of neural stem cells and glial cells, preserving cell viability and function while minimizing immune rejection. These properties make alginate an ideal candidate for developing bioengineered neural tissues, in vitro brain models, and regenerative therapies aimed at restoring damaged neural circuits. As research advances, alginate continues to emerge as a key biomaterial in the design of next-generation neurotherapeutic strategies, offering promising avenues for both fundamental neuroscience and translational applications in neurodegenerative disease treatment.
Host:
Mouse
Immunogen:
Sodium Alginate conjugated to KLH
Isotype:
IgG1, kappa
Purification:
Protein G Purified
Reactivities:
Wide/Non-species Specific
Shipping Conditions:
Blue Ice
Specificity:
Binds selectively to a BSA-conjugated alginate, but not to unconjugated BSA.
Storage Conditions:
See Manual
Supplier:
StressMarq Biosciences
Type:
Antibody: Monoclonal Antibody