CENP-A Antibody, Clone 5A7-2E11: PerCP
Product Sizes
100 ug
SMC-202D-PCP-100UG
About this Product
- SKU:
- SMC-202D-PCP
- Additional Names:
- CENP A Antibody, cenpa Antibody, Centromere auto antigen A Antibody, Histone H3 like centromeric protein A Antibody
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 5A7-2E11
- Clonality:
- Monoclonal
- Conjugate:
- PerCP
- Concentration:
- 1 mg/ml
- Extra Details:
- A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The Centromere Protein-A, CENP-A, is a Histone H3-like protein that contains a C-terminal H3-like domain, which is required for centromere localization of CENP-A, and an antigenic N-terminal domain. CENP-A, originally isolated from HeLa cells, is essential for kinetochore targeting of CENP-C. In the presence of DNA CENP-A forms an octa-meric complex with histones H4, H2A, H2B. CENP-A specifically localizes to active centromeres and is a component of specialized centromeric nucleosomes, on which kinetochores are assembled. CENP-A is essential for nucleosomal packaging of centromeric DNA at interphase and functions as a centromere formation marker on the chromosome.
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to a portion of human CENP-A
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects ~18kDa. Recognizes Human CENP-A.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
