DUX4 Antibody, Clone P2B1: ATTO 390
Product Sizes
100 ug
SMC-192D-A390-100UG
About this Product
- SKU:
- SMC-192D-A390
- Additional Names:
- Double homeobox 4 Antibody, Double homeobox 10 Antibody, DUX10 Antibody, Double homeobox protein 4/10 Antibody, DUX4L antibody, DUX4L1 antibody
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- CE/IVD:
- RUO
- translate.label.attr.clone:
- P2B1
- Clonality:
- Monoclonal
- Conjugate:
- ATTO 390
- Concentration:
- 1 mg/ml
- Extra Details:
- DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
- Host:
- Mouse
- Immunogen:
- C-terminal 76 amino acids of Human DUX4 with glutathione-s-transferase (gst) tag
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects ~45kDa. No cross-reactivity with DUX4c.
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Type:
- Antibody: Monoclonal Antibody
