Corticosterone EIA Kit
Product Sizes
96 wells
£364.00
SKT-205-96WELLS
About this Product
- SKU:
- SKT-205
- Additional Names:
- (11B Beta)-11,21-dihydroxypregn-4-ene-3,20-dione
- CE/IVD:
- RUO
- Extra Details:
- Corticosterone (C₂₁H₃₀O₄) is a glucocorticoid hormone secreted by the adrenal cortex in response to ACTH stimulation. It is the primary stress hormone in rodents and a precursor to aldosterone. In neuroscience research, corticosterone is widely used to model chronic stress and its effects on brain function. Elevated corticosterone levels have been shown to impair memory retrieval, alter sleep-wake cycles, and exacerbate neurodegenerative processes. In Parkinson's disease models, chronic corticosterone exposure increases alpha-synuclein phosphorylation and aggregation, particularly in the hypothalamus, and contributes to dopaminergic neuron loss. These findings highlight corticosterone's role in stress-induced neurotoxicity and its relevance in studying the pathophysiology of neurodegenerative and psychiatric disorders.
- Format:
- Colorimetric
- Immunogen:
- Corticosterone EIA Kit
- Physical State:
- Cell Culture Supernatant, Feces, Plasma, Serum, Urine
- Range:
- 78.125 - 10,000 pg/ml
- Reactivities:
- Wide/Non-species Specific
- Sensitivity:
- 18.6 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C, -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Assay Kits: ELISAs
