XIB4035
Product Sizes
5 mg
£169.00
SIH-646-5MG
25 mg
£466.00
SIH-646-25MG
About this Product
- SKU:
- SIH-646
- Additional Names:
- (E)-N4-(7-chloro-2-(2-chlorostyryl)quinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine, 3(H3PO4)
- CAS Number:
- 10023-54-8
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- XIB4035 is a small-molecule GFRA Alpha1 agonist and GDNF pathway modulator with neuroprotective and neuroregenerative activity. It activates RET signaling and promotes neurite outgrowth, mimicking key effects of the neurotrophic factor GDNF. The GDNF-GFRA Alpha1-RET pathway is highly relevant to neurodegeneration research. In a Parkinson's disease mouse model, RET was shown to be essential for the neuroprotective and neuroregenerative effects of GDNF, supporting the use of XIB4035 as a tool to study neuronal survival and repair mechanisms.
- Molecular Weight:
- 750.4
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/agonist/xib4035-sih-646/
