CBA
Product Sizes
5 mg
£171.00
SIH-633-5MG
25 mg
£412.00
SIH-633-25MG
About this Product
- SKU:
- SIH-633
- Additional Names:
- 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid; TRPM4-IN-5
- CAS Number:
- 351424-20-9
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- CBA is a selective blocker of TRPM4 channels (IC50 = 1.5 uM), with no activity at related TRP channels or other ion channels. It has demonstrated neuroprotective effects in models of glutamate-induced neuronal degeneration and experimental autoimmune encephalomyelitis, a model of multiple sclerosis. By modulating TRPM4 activity, CBA provides a valuable tool for investigating calcium-independent cation flux in neurons and glial cells, and its role in neuroinflammation and neurodegeneration. Its specificity and in vivo efficacy make it a promising candidate for therapeutic exploration in CNS disorders.
- Molecular Weight:
- 340.2
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/blocker/cba-sih-633/
