SGI-1027
Product Sizes
5 mg
£182.00
SIH-596-5MG
25 mg
£551.00
SIH-596-25MG
About this Product
- SKU:
- SIH-596
- Additional Names:
- N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide
- CAS Number:
- 1020149-73-8
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- SGI-1027 is a small-molecule inhibitor of DNA methyltransferases (DNMTs), including DNMT1, DNMT3A, and DNMT3B. It interferes with epigenetic regulation by blocking DNA methylation, thereby reactivating silenced genes. In neurodegenerative disease research, SGI-1027 is of interest for its potential to modulate gene expression patterns associated with neuronal survival, synaptic plasticity, and neuroinflammation. Epigenetic dysregulation is a hallmark of several CNS disorders, and DNMT inhibitors like SGI-1027 may offer therapeutic avenues for restoring normal gene function.
- Molecular Weight:
- 461.5
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/sgi-1027-sih-596/
