Nelfinavir mesylate
Product Sizes
5 mg
£145.00
SIH-586-5MG
25 mg
£348.00
SIH-586-25MG
About this Product
- SKU:
- SIH-586
- Additional Names:
- (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonate; AG-1343
- CAS Number:
- 159989-65-8
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Nelfinavir mesylate, originally developed as an HIV protease inhibitor, has gained attention for its broader biological effects, including autophagy induction and anti-cancer activity. It modulates the Akt/PKB signaling pathway and triggers endoplasmic reticulum stress, leading to activation of the unfolded protein response. These mechanisms are increasingly relevant in neurodegenerative disease research, where protein misfolding, ER stress, and impaired autophagy are central features. Nelfinavir's ability to influence these pathways positions it as a potential candidate for repurposing in neurodegenerative disorders such as Alzheimer's and Parkinson's disease.
- Molecular Weight:
- 663.9
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/nelfinavir-mesylate-sih-586/
