Zebularine
Product Sizes
5 mg
£132.00
SIH-560-5MG
25 mg
£348.00
SIH-560-25MG
About this Product
- SKU:
- SIH-560
- Additional Names:
- 1H-B Beta-D-ribofuranosyl-2-pyrimidinone, NSC 309132, 1-(B Beta-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one, 2-Pyrimidone-1-B Beta-D-riboside, 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, 4-deoxyuridine, NSC 309132, pyrimidin-2-one beta-D-ribofuranoside, pyrimidin-2-one beta-ribofuranoside, pyrimidin-2-one beta-ribofuranoside, (L)-isomer, pyrimidin-2-one ribonucleoside, zebularine, Pyrimidin-2-one ribonucleoside, Pyrimidin-2-one beta-ribofuranoside, Pyrimidin-2-one beta-D-ribofuranoside
- CAS Number:
- 3690-10-6
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Zebularine is a DNA methyltransferase (DNMT) inhibitor that induces DNA hypomethylation and reactivates silenced genes. In neurodegenerative disease research, Zebularine is used to explore the role of epigenetic modifications in neuronal plasticity, memory, and neuroinflammation. It is particularly relevant in studies of Alzheimer's disease, where aberrant DNA methylation contributes to gene silencing and synaptic dysfunction. Zebularine's stability and low toxicity make it a useful tool for investigating epigenetic therapies in the central nervous system.
- Molecular Weight:
- 228.2
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/zebularine-sih-560/
