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Product Sizes
1 mg
£211.00
SIH-557-1MG
About this Product
SKU:
SIH-557
Additional Names:
ZVAD-FMK, Z-VAD-FMK, Caspase Inhibitor I, Z-VAD (OMe)-FMK, Z-VAD(OMe)-FMK, Ac-ZVAD-FMK, benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone, carbobenzoxyvalyl-alanyl-aspartyl fluoromethyl ketone, FK 009, FK-009, FK009, Z-VAD.FMK, Z-Val-Ala-Asp-fluoromethylketone, ZVAD-fluoromethylketone, methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate
CAS Number:
187389-52-2
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
Z-VAD-FMK is a broad-spectrum, irreversible pan-caspase inhibitor that blocks apoptosis by inhibiting caspase activation. In neuroscience, it is used to investigate the role of programmed cell death in neurodegenerative diseases, traumatic brain injury, and ischemic stroke. By preventing caspase-mediated neuronal apoptosis, Z-VAD-FMK helps delineate the molecular pathways involved in cell death and survival. It is also employed to study neuroinflammation and glial responses, making it a critical tool for exploring therapeutic interventions aimed at preserving neuronal integrity.
Molecular Weight:
467.49
Purity:
>98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors