Carfilzomib
Product Sizes
5 mg
£151.00
SIH-544-5MG
25 mg
£389.00
SIH-544-25MG
About this Product
- SKU:
- SIH-544
- Additional Names:
- (A AlphaS)-A Alpha-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide, PR-17, Carfilzomib, Kyprolis, Carfilzomib (PR-171), PR-171, UNII-72X6E3J5AR
- CAS Number:
- 868540-17-4
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Carfilzomib is an irreversible proteasome inhibitor that selectively targets the chymotrypsin-like activity of the 20S proteasome. While primarily developed as an anticancer agent, Carfilzomib has relevance in neurodegenerative disease research due to its impact on protein homeostasis. By modulating the ubiquitin-proteasome system, Carfilzomib helps elucidate mechanisms of protein aggregation and clearance, which are central to diseases like Alzheimer's, Parkinson's, and ALS. Its role in inducing apoptosis and cell cycle arrest also provides insights into neuronal vulnerability and stress responses.
- Molecular Weight:
- 719.9
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/carfilzomib-sih-544/
