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Product Sizes
5 mg
£145.00
SIH-542-5MG
25 mg
£389.00
SIH-542-25MG
About this Product
SKU:
SIH-542
Additional Names:
NSC59984, NSC-59984, NSC59984, MLS000737358, SMR000528276, (E)-1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one, 803647-40-7, AC1NS9AU, CID 5356520, MLS000737358, 1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine, 1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one
CAS Number:
803647-40-7
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
NSC59984 is a small molecule that restores wild-type p53 signaling in tumor cells by modulating the mutant p53/MDM2 pathway. Although its primary application is in oncology, the compound's ability to influence p53-mediated apoptosis and DNA repair pathways may have relevance in neurodegenerative disease models, where p53 dysregulation contributes to neuronal loss. Its selective cytotoxicity in cancer cells while sparing healthy cells also highlights its potential for targeted therapeutic development.
Molecular Weight:
265.3
Purity:
>98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors