Tolcapone
Product Sizes
10 mg
£151.00
SIH-540-10MG
50 mg
£382.00
SIH-540-50MG
About this Product
- SKU:
- SIH-540
- Additional Names:
- (3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone, Tolcapone, Tasmar, Ro 40-7592
- CAS Number:
- 134308-13-7
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Tolcapone is a potent catechol-O-methyltransferase (COMT) inhibitor that enhances dopaminergic signaling by preventing dopamine degradation. It is clinically used in Parkinson's disease and has demonstrated neuroprotective effects by inhibiting alpha-synuclein and beta-amyloid aggregation. Tolcapone also binds transthyretin (TTR), stabilizing it and preventing TTR-induced cytotoxicity. These multifaceted actions make Tolcapone a valuable compound in neurodegenerative disease research, particularly in Parkinson's and Alzheimer's disease models.
- Molecular Weight:
- 273.2
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/tolcapone-sih-540/
